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Wednesday, November 25, 2009

aman

What killed Ranjan Das and Lessons for Corporate India




A month ago, many of us heard about the sad demise of Ranjan Das from Bandra, Mumbai. Ranjan, just 42 years of age, was the CEO of SAP-Indian Subcontinent, the youngest CEO of an MNC in India . He was very active in sports, was a fitness freak and a marathon runner. It was common to see him run on Bandra's Carter Road . Just after Diwali, on 21st Oct, he returned home from his gym after a workout, collapsed with a massive heart attack and died. He is survived by his wife and two very young kids.

It was certainly a wake-up call for corporate India . However, it was even more disastrous for runners amongst us. Since Ranjan was an avid marathoner ( in Feb 09, he ran Chennai Marathon at the same time some of us were running Pondicherry Marathon 180 km away ), the question came as to why an exceptionally active, athletic person succumb to heart attack at 42 years of age.

Was it the stress?

A couple of you called me asking about the reasons. While Ranjan had mentioned that he faced a lot of stress, that is a common element in most of our lives. We used to think that by being fit, one can conquer the bad effects of stress. So I doubted if the cause was stress.

The Real Reason

However, everyone missed out a small line in the reports that Ranjan used to make do with 4-5 hours of sleep. This is an earlier interview of Ranjan on NDTV in the program 'Boss' Day Out': Boss' Day Out: Ranjan Das of SAP India.

Here he himself admits that he would love to get more sleep ( and that he was not proud of his ability to manage without sleep, contrary to what others extolled ).

The Evidence

Last week, I was working with a well-known cardiologist on the subject of 'Heart Disease caused by Lack of Sleep'. While I cannot share the video nor the slides because of confidentiality reasons, I have distilled the key points below in the hope it will save some of our lives.

Some Excerpts:

· Short sleep duration ( <5 or 5-6 hours ) increased risk for high BP by 350% to 500% compared to those who slept longer than 6 hours per night. Paper published in 2009. As you know, high BP kills.

· Young people ( 25-49 years of age ) are twice as likely to get high BP if they sleep less. Paper published in 2006.

· Individuals who slept less than 5 hours a night had a 3-fold increased risk of heart attacks. Paper published in 1999.

· Complete and partial lack of sleep increased the blood concentrations of High sensitivity C-Reactive Protein (hs-cRP), the strongest predictor of heart attacks. Even after getting adequate sleep later, the levels stayed high!!

· Just one night of sleep loss increases very toxic substances in body such as Interleukin-6 (IL-6), Tumour Necrosis Factor-Alpha (TNF-alpha) and C-reactive protein (cRP). They increase risks of many medical conditions, including cancer, arthritis and heart disease. Paper published in 2004.

· Sleeping for <=5 hours per night leads to 39% increase in heart disease. Sleeping for <=6 hours per night leads to 18% increase in heart disease. Paper published in 2006.

Ideal Sleep

For lack of space, I cannot explain here the ideal sleep architecture. But in brief, sleep is composed of two stages: REM ( Rapid Eye Movement ) and non-REM. The former helps in mental consolidation while the latter helps in physical repair and rebuilding. During the night, you alternate between REM and non-REM stages 4-5 times.

The earlier part of sleep is mostly non-REM. During that period, your pituitary gland releases growth hormones that repair your body. The latter part of sleep is more and more REM type.

For you to be mentally alert during the day, the latter part of sleep is more important. No wonder when you wake up with an alarm clock after 5-6 hours of sleep, you are mentally irritable throughout the day (lack of REM sleep). And if you have slept for less than 5 hours, your body is in a complete physical mess ( lack of non-REM sleep ), you are tired throughout the day, moving like a zombie and your immunity is way down ( I've been there, done that ).

Finally, as long-distance runners, you need an hour of extra sleep to repair the running related damage.

If you want to know if you are getting adequate sleep, take Epworth Sleepiness Test below.

Interpretation: Score of 0-9 is considered normal while 10 and above abnormal. Many a times, I have clocked 21 out the maximum possible 24, the only saving grace being the last situation, since I don't like to drive ( maybe, I should ask my driver to answer that line ).

In conclusion:

Barring stress control, Ranjan Das did everything right: eating proper food, exercising ( marathoning! ), maintaining proper weight. But he missed getting proper and adequate sleep, minimum 7 hours. In my opinion, that killed him.
If you are not getting enough sleep ( 7 hours ), you are playing with fire, even if you have low stress.

I always took pride in my ability to work 50 hours at a stretch whenever the situation warranted. But I was so spooked after seeing the scientific evidence last week that since Saturday night, I ensure I do not even set the alarm clock under 7 hours. Now, that is a nice excuse to get some more sleep.

Unfortunately, Ranjan Das is not alone when it comes to missing sleep. Many of us are doing exactly the same, perhaps out of ignorance. Please forward this mail/article to as many of your colleagues/friends as possible, especially those who might be short-changing their sleep. If we can save even one young life because of this email, I would be the happiest person on earth.

Thursday, November 12, 2009

aman

French ban on Red Bull (drink) upheld by European Court


Health concerns over the Red Bull energy drink were fuelled yesterday after Europe's highest court upheld a French ban on the product.

The fizzy drink has been linked to several deaths and some experts have criticised its high levels of caffeine and other stimulants.

Red Bull is Britain's best-selling energy drink, with 213 million cans consumed last year. It has been dubbed the 'clubbers' drink', and is often mixed with vodka. The popular adverts claiming that Red Bull 'gives you wings', have led to the brand being described as 'the Porsche of soft drinks'.


It contains caffeine, vitamins, and sugar which, the company claims, kick-starts the body's metabolism and keeps people alert. But France has refused to authorise its sale, along with other vitamin-fortified foods such as Danone yoghurt and Kellogg's cereals.

The European Commission (EC) challenged France's ban after manufacturers complained it was inhibiting imports.

In a ruling yesterday, the European Court of Justice upheld the main part of the EC challenge, ordering France to lift the ban unless it could prove the health risks. But the court said that the French government did have a right to ban Red Bull.

The judges said that a study by the French Scientific Committee on Human Nutrition found that Red Bull contained excessive caffeine. The committee also raised concerns about the drink's other ingredients - taurine, an amino acid the company claims can 'kick-start' the metabolism - and glucuronolactone, a carbohydrate.

The EC's Scientific Committee on Food conducted a study last year, and found that while caffeine levels in energy drinks were safe, more studies were needed to assess the dangers of taurine and glucuronolactone.

While other toxicology experts had concluded that the caffeine levels in Red Bull are safe, France had a right to ban the drink on the advice of its own experts, the court said.

One can of Red Bull contains 80mg of caffeine - equivalent to one cup of coffee. Three years ago, Ross Cooney, 18, from Ireland, died after he shared four cans of Red Bull and played in a basketball match.


An inquest into his death ruled that he died from Sudden Adult Death Syndrome.

Lyndel Costain, a dietician, said: 'The problem with caffeine is that the effects can vary, so it is difficult to say what is a safe level. High levels of caffeine can be dangerous for people with high blood pressure or anxiety disorders. Not much is known about taurine and glucuronolactone, but high levels of them could affect the body.'

Red Bull - which sells 1.6 billion cans worldwide - said yesterday that its product was safe.

A spokeswoman said: 'Red Bull will continue to be sold in 100 countries worldwide.' She added: 'No authority in the world has ever discovered or proven an unhealthy effect in or from Red Bull.'

Only France, Denmark and Norway have banned the drink. Britain's Committee on Toxicity investigated Red Bull in 2001 and found that it was safe, but warned pregnant women against it because high caffeine intake has been linked to a risk of miscarriage.

An EU ruling which comes into force this year means that Red Bull and other energy drinks will have to carry 'high caffeine content' warnings. An urban myth that taurine was made from bull's semen has only added to its popularity.

Safety fears Ross Cooney, 18, was a healthy basketball player, but died in 2000 just hours after drinking Red Bull.

The student from Limerick, Ireland, died after sharing four cans of the drink with friends before a basketball game.

At his inquest, the coroner called officials from the Austrian-based company to give evidence about their product. They said that no adverse effects had been proven in connection with the drink.

The inquest jury later ruled that the teenager had died as a result of Sudden Adult Death Syndrome, but called for an inquiry into high-caffeine energy drinks.

A Brazilian study found that those who mix Red Bull with alcohol may be drunker than they think they are - the energy drink may mask the alcohol effect.

-- How good are these energy drinks?
-- The Perils Of Mixing Energy Drinks With Alcohol
-- Scientists Close In On Taurine's Activity In The Brain

Written by - Christian Nordqvist